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Centrifuge experiment and numerical analysis of an air-backed plate subjected to underwater shock loading

Zhijie HUANG, Xiaodan REN, Zuyu CHEN, Daosheng LING

《结构与土木工程前沿（英文）》 2019年 第13卷 第6期   页码 1350-1362 doi: 10.1007/s11709-019-0559-x

摘要： In this study, systematic centrifuge experiments and numerical studies are conducted to investigate the effect of shock loads due to an underwater explosion on the dynamic responses of an air-backed steel plate. Numerical simulations with three different models of pressure time history generated by underwater explosion were carried out. The first model of pressure time history was measured in test. The second model to predict the time history of shock wave pressure from an underwater explosion was created by Cole in 1948. Coefficients of Cole’s formulas are determined experimentally. The third model was developed by Zamyshlyaev and Yakovlev in 1973. All of them are implemented into the numerical model to calculate the shock responses of the plate. Simulated peak strains obtained from the three models are compared with the experimental results, yielding average relative differences of 21.39%, 45.73%, and 13.92%, respectively. The Russell error technique is used to quantitatively analyze the correlation between the numerical and experimental results. Quantitative analysis shows that the simulated strains for most measurement points on the steel plate are acceptable. By changing the scaled distances, different shock impulses were obtained and exerted on the steel plate. Systematic numerical studies are performed to investigate the effect of the accumulated shock impulse on the peak strains. The numerical and experimental results suggest that the peak strains are strongly dependent on the accumulated shock impulse.

关键词： underwater explosion     centrifuge experiment     shock load     dynamic response     accumulated shock impulse    

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Beneficial effect of arginine vasopressin on hemorrhagic shock through improving the vascular reactivity

LI Tao, YANG Guangming, XU Jing, LIU Jiancang, LIU Liangming

《医学前沿（英文）》 2008年 第2卷 第3期   页码 248-254 doi: 10.1007/s11684-008-0047-5

摘要： The vascular reactivity and calcium sensitivity were decreased following hemorrhagic shock. Arginine vasopressin (AVP) was beneficial to endotoxic, infectious/septic and hemorrhagic shock. Our previous studies found that Rho kinase played an important role in the occurrence of calcium desensitization following shock. It was reported that AVP was with stimulation effect of Rho kinase. So we hypothesized that AVP might have beneficial effect on shock via activation of Rho kinase to regulate the calcium sensitivity and vascular reactivity. Hemorrhagic shock (40 mmHg for 2 h) Wistar rats were adopted to observe the effects of small dose of AVP on hemodynamics, 24-h survival rate, the pressor effect of norepinephrine (NE) and the contractility of superior mesenteric artery (SMA). Isolated SMAs from hemorrhagic shock rats were adopted to observe the effects of AVP on vascular reactivity and calcium sensitivity and its relationship to Rho kinase with an isolated organ perfusion system. The results show that AVP at the concentration of 0.1 U/kg and 0.4 U/kg significantly improved the hemodynamic parameters and the 24-h survival rate of hemorrhagic shock rats. Meanwhile, these dosages of AVP significantly increased the pressor effect of NE and the contractile response of SMA to NE. Y-27632 (3 ?g/kg), a Rho kinase specific inhibitor, abolished the beneficial effects of AVP. , the calcium sensitivity and vascular reactivity of SMA to calcium and NE were significantly decreased following hemorrhagic shock. AVP at the concentration of 0.5 nmol/L and 5 nmol/L significantly increased the calcium sensitivity and vascular reactivity. These effects of AVP were abolished by Y-27632 (10 ?mol/L). Taken together, the results suggest that AVP at 0.1 U/kg and 0.4 U/kg is beneficial to hemorrhagic shock by improving the vascular reactivity, which involves activation of Rho kinase.
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Expression of heat shock protein gp96 in osteosarcoma and its clinical significance

GUO Weichun, CHEN Anmin

《医学前沿（英文）》 2008年 第2卷 第2期   页码 200-203 doi: 10.1007/s11684-008-0038-6

摘要： This study aims to detect the expression of heat shock protein gp96 (HSPgp96) in osteosarcoma and explore its role in anti-tumor immunity. Expression of HSPgp96 in 45 cases of osteosarcoma, including 24 cases of the osteoblast type, 21 cases of chondroblast type and 5 cases of normal bone tissue were detected by immunohistochemistry (IHC). The expression rate of HSPgp96 was 100% (45/45) in osteosarcoma, compared with 20% (1/5) in normal bone tissue. The average positive cell rates were 97.23% and 0.48% in osteosarcoma and normal bone tissue, respectively, and the difference between them was significant ( < 0.01). The positive cell rates in osteoblast type and chondroblast type were 97.78% and 96.56%, respectively, and the difference had no statistical significance ( > 0.05). The expression degree of HSPgp96 in osteosarcoma had a clear correlation with the pathologic degree ( < 0.05), while it had no relationship with the clinical stage ( > 0.05). The expression of HSPgp96 is high in osteosarcoma and it may be a significant index for judgment of malignancy degree and an important target site of anti-tumor immunity.
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Influence evaluation of loading conditions during pressurized thermal shock transients based on thermal-hydraulics

Jinya KATSUYAMA, Shumpei UNO, Tadashi WATANABE, Yinsheng LI

《机械工程前沿（英文）》 2018年 第13卷 第4期   页码 563-570 doi: 10.1007/s11465-018-0487-9

摘要：

The thermal hydraulic (TH) behavior of coo-lant water is a key factor in the structural integrity assessments on reactor pressure vessels (RPVs) of pressurized water reactors (PWRs) under pressurized thermal shock (PTS) events, because the TH behavior may affect the loading conditions in the assessment. From the viewpoint of TH behavior, configuration of plant equipment and their dimensions, and operator action time considerably influence various parameters, such as the temperature and flow rate of coolant water and inner pressure. In this study, to investigate the influence of the operator action time on TH behavior during a PTS event, we developed an analysis model for a typical Japanese PWR plant, including the RPV and the main components of both primary and secondary systems, and performed TH analyses by using a system analysis code called RELAP5. We applied two different operator action times based on the Japanese and the United States (US) rules: Operators may act after 10 min (Japanese rules) and 30 min (the US rules) after the occurrence of PTS events. Based on the results of TH analysis with different operator action times, we also performed structural analyses for evaluating thermal-stress distributions in the RPV during PTS events as loading conditions in the structural integrity assessment. From the analysis results, it was clarified that differences in operator action times significantly affect TH behavior and loading conditions, as the Japanese rule may lead to lower stresses than that under the US rule because an earlier operator action caused lower pressure in the RPV.

关键词： structural integrity     reactor pressure vessel     pressurized thermal shock     thermal hydraulic analysis     pressurized water reactor     weld residual stress    

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Alteration of heat shock protein 20 expression in preeclamptic patients and its effect in vascular and

Fanfan Li, Mengzhou He, Meitao Yang, Yao Fan, Yun Chen, Xi Xia, Yin Xie, Dongrui Deng

《医学前沿（英文）》 2018年 第12卷 第5期   页码 542-549 doi: 10.1007/s11684-017-0576-x

摘要：

Preeclampsia (PE) is a pregnancy-specific, multi-system disorder and the leading cause of maternal and perinatal morbidity and mortality in obstetrics worldwide. Excessive vasoconstriction and dysregulated coagulation function are closely associated with PE. Heat shock protein 20 (HSP20) is ubiquitously expressed under normal physiological conditions and has important roles in vascular dilatation and suppression of platelet aggregation. However, the role of HSP20 in the pathogenesis of PE remains unclear. In this study, we collected chorionic plate resistance arteries (CPAs) and serum from 118 healthy pregnant women and 80 women with PE and detected the levels of HSP20 and its phosphorylated form. Both HSP20 and phosphorylated HSP20 were downregulated in CPAs from women with PE. Comparison of the vasodilative ability of CPAs from the two groups showed impaired relaxation responses to acetyl choline in preeclamptic vessels. In addition to the reduced HSP20 in serum from women with PE, the platelet distribution width and mean platelet volume were also decreased, and the activated partial thromboplastin time and thromboplastin time were elevated. With regard to the vital roles of HSP20 in mediating vasorelaxation and coagulation function, the decreased HSP20 might contribute to the pathogenesis of PE.

关键词： preeclampsia     heat shock protein 20     vascular relaxation     coagulation-fibrinolytic system    

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Estimation of composite load model with aggregate induction motor dynamic load for an isolated hybrid

Nitin Kumar SAXENA,Ashwani Kumar SHARMA

《能源前沿（英文）》 2015年 第9卷 第4期   页码 472-485 doi: 10.1007/s11708-015-0373-7

摘要： It is well recognized that the voltage stability of a power system is affected by the load model and hence, to effectively analyze the reactive power compensation of an isolated hybrid wind-diesel based power system, the loads need to be considered along with the generators in a transient analysis. This paper gives a detailed mathematical modeling to compute the reactive power response with small voltage perturbation for composite load. The composite load is a combination of the static and dynamic load model. To develop this composite load model, the exponential load is used as a static load model and induction motors (IMs) are used as a dynamic load model. To analyze the dynamics of IM load, the fifth, third and first order model of IM are formulated and compared using differential equations solver in Matlab coding. Since the decentralized areas have many small consumers which may consist large numbers of IMs of small rating, it is not realistic to model either a single large rating unit or all small rating IMs together that are placed in the system. In place of using a single large rating IM, a group of motors are considered and then the aggregate model of IM is developed using the law of energy conservation. This aggregate model is used as a dynamic load model. For different simulation studies, especially in the area of voltage stability with reactive power compensation of an isolated hybrid power system, the transfer function of the composite load is required. The transfer function of the composite load is derived in this paper by successive derivation for the exponential model of static load and for the fifth and third order IM dynamic load model using state space model.

关键词： isolated hybrid power system (IHPS)     composite load model     static load     dynamic load     induction motor load model     aggregate load    

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岩石冲击损伤演化规律数值流形方法模拟

刘红岩,吕淑然,秦四清

《中国工程科学》 2007年 第9卷 第3期   页码 92-96

摘要：

采用应力波衰减损伤模型对仅适用于模拟基于线性本构关系和恒定载荷作用下物体变形规律的数值 流形程序进行了扩展；利用扩展后的程序对岩石长杆在冲击载荷作用下的损伤演化规律进行了模拟，得出了不 同位置点处的损伤演化曲线和材料总体的损伤演化曲线。模拟结果表明，损伤的增加主要集中在冲击载荷作用的初始阶段，随着时间的推移，应力波强度衰减，损伤将不再明显增加。

关键词： 岩石     数值流形方法     冲击损伤     演化规律    

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Effects on mechanical properties in electron beam welding of TC4 alloy by laser shock processing

LU Jinzhong, ZHANG Yongkang, KONG Dejun, REN Xudong, GE Tao, ZOU Shikun

《机械工程前沿（英文）》 2007年 第2卷 第4期   页码 478-482 doi: 10.1007/s11465-007-0083-x

摘要： The surface of TC4 titanium alloy welding line by electron beam welding (EBW) was processed by high power Q-switched and repetition-rate Nd: glass laser. Effects of laser power and spot diameter on residual stress and micro-hardness of the TC4 alloy welding line by laser shock processing (LSP) have been analyzed. Results show that residual stresses almost do not change as laser power is 45.9 J, spot diameter is φ9 mm; While laser power is 45.9 J, spot diameter less than φ3 mm, the distribution of residual stress in welding line occurs obvious variation, which residual stress increase obviously with spot diameter decrease. When power density is bigger than 1.8×10 W/cm, residual stresses of electron beam welding line occur change by LSP, which improve obviously residual stress distribution; while laser power is bigger than 1.2×10 W/cm, the surface micro-hardness of electron beam welding line occurs change by LSP, which improve obviously micro-hardness distribution. Mechanical properties of TC4 titanium alloy welding line will be improved by LSP, which provides experimental foundation for further controlling the distributions of residual stress and micro-hardness during laser shock processing.
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Calculation method of load distribution on pipe threaded connections under tension load

Shoujun CHEN, Lianxin GAO, Qi AN

《机械工程前沿（英文）》 2011年 第6卷 第2期   页码 241-248 doi: 10.1007/s11465-011-0219-x

摘要：

This paper presents a new calculation method that can calculate the load distribution on pipe threaded connections under tension load. On the basis of elastic mechanics, the new method was developed by analyzing each thread tooth, and a new deformation and covariant equation by making a mechanics analysis on each thread tooth was obtained. Compared with the traditional method proposed by the previous references, the new deformation and covariant equation could be used to describe the relation between the previous and the next thread tooth. By applying the new method on the sample of P-110S pipe threaded connection, the obtained results show that the load on thread tooth mainly concentrates on the four or five threads engaged and the middle teeth were not utilized well to bear the loads. The model offers a new way to calculate the loads carried on the thread teeth under tension load.

关键词： load distribution     calculation method     pipe threaded connections     tension load    

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水下钻孔爆破的爆炸冲击波测试与分析

柯松林,李琳娜,司剑峰,钟冬望

《中国工程科学》 2014年 第16卷 第11期   页码 103-106

摘要：

以厦门港古雷航道水下炸礁为例，分析了水下钻孔爆破的水击波形成特征，并通过爆破区的水中冲击波压力监测，实测了不同距离处的水击波压力大小和变化规律，研究了水中冲击波压力幅值、正压作用时间等作用特性，得到了水击波传播衰减公式。研究成果对指导工程设计施工和环境安全评估具有参考意义。

关键词： 水下钻孔爆破     水中冲击波     压力特性    

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Comparison of optimal capacitor placement methods in radial distribution system with load growth andZIP load model

Veera Venkata Satya Naryana MURTY, Ashwani KUMAR

《能源前沿（英文）》 2013年 第7卷 第2期   页码 197-213 doi: 10.1007/s11708-013-0249-7

摘要： In this paper, a combined power loss sensitivity (PLS) index-based approach is proposed to determine the optimal location of the capacitors in the radial distribution system (RDS) based on the real and reactive combined loss sensitivity index, as capacitor placement not only reduces real power loss with voltage profile improvement but also reduces reactive power loss due to the reactive power compensation in the network. The results have been obtained with the existing methods of power loss index (PLI) and index vector (IV) method for comparison. Besides, the optimal placement has been obtained with the proposed method as well as existing methods and the total kVar support has been obtained. In addition, the results of net cost savings for the 10-, 34-, and 69-bus systems are obtained for comparison. Moreover, the results have been obtained for a large system of 85 buses to validate the results with combined sensitivity based approach. Furthermore, the load growth factor has been considered in the study which is essential for the planning and expansion of the existing systems, whereas the impact of the realistic load model as ZIP load model has been considered for the study of all the systems.

关键词： load growth     load models     reactive power compensation     radial distribution system     power loss index (PLI)     power loss sensitivity (PLS)     index vector (IV)    

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化爆冲击波在90°拐角通道内的到时规律

沈俊,李永池,庞伟宾,

《中国工程科学》 2006年 第8卷 第3期   页码 53-57

摘要：

对空气冲击波在90°拐角坑道内传播的到时规律及其影响因素进行了实验研究，在无量纲分析基础上建立了简化的工程模型。通过对实验数据拟合建立了可以对高能炸药在90°拐角坑道内爆炸产生的空气冲击波到达时间进行预计的公式，利用该公式可以进一步求得空气冲击波在90°拐角坑道内的传播速度。

关键词： 内爆炸     冲击波     到时    

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A practical multi-lane factor model of bridges based on multi-truck presence considering lane load disparities

《结构与土木工程前沿（英文）》 2021年 第15卷 第4期   页码 877-894 doi: 10.1007/s11709-021-0756-2

摘要： Many bridge design specifications consider multi-lane factors (MLFs) a critical component of the traffic load model. Measured multi-lane traffic data generally exhibit significant lane disparities in traffic loads over multiple lanes. However, these disparities are not considered in current specifications. To address this drawback, a multi-coefficient MLF model was developed based on an improved probabilistic statistical approach that considers the presence of multiple trucks. The proposed MLF model and approach were calibrated and demonstrated through an example site. The model sensitivity analysis demonstrated the significant influence of lane disparity of truck traffic volume and truck weight distribution on the MLF. Using the proposed approach, the experimental site study yielded MLFs comparable with those directly calculated using traffic load effects. The exclusion of overloaded trucks caused the proposed approach, existing design specifications, and conventional approach of ignoring lane load disparity to generate comparable MLFs, while the MLFs based on the proposed approach were the most comprehensive. The inclusion of overloaded trucks caused the conventional approach and design specifications to overestimate the MLFs significantly. Finally, the benefits of the research results to bridge practitioners were discussed.

关键词： bridges     multi-lane factor     traffic load     lane load disparity     multi-truck presence     weigh-in-motion data    

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Shape design of arch dams under load uncertainties with robust optimization

Fengjie TAN, Tom LAHMER

《结构与土木工程前沿（英文）》 2019年 第13卷 第4期   页码 852-862 doi: 10.1007/s11709-019-0522-x

摘要： Due to an increased need in hydro-electricity, water storage, and flood protection, it is assumed that a series of new dams will be build throughout the world. The focus of this paper is on the non-probabilistic-based design of new arch-type dams by applying means of robust design optimization (RDO). This type of optimization takes into account uncertainties in the loads and in the material properties of the structure. As classical procedures of probabilistic-based optimization under uncertainties, such as RDO and reliability-based design optimization (RBDO), are in general computationally expensive and rely on estimates of the system’s response variance, we will not follow a full-probabilistic approach but work with predefined confidence levels. This leads to a bi-level optimization program where the volume of the dam is optimized under the worst combination of the uncertain parameters. As a result, robust and reliable designs are obtained and the result is independent from any assumptions on stochastic properties of the random variables in the model. The optimization of an arch-type dam is realized here by a robust optimization method under load uncertainty, where hydraulic and thermal loads are considered. The load uncertainty is modeled as an ellipsoidal expression. Comparing with any traditional deterministic optimization method, which only concerns the minimum objective value and offers a solution candidate close to limit-states, the RDO method provides a robust solution against uncertainty. To reduce the computational cost, a ranking strategy and an approximation model are further involved to do a preliminary screening. By this means, the robust design can generate an improved arch dam structure that ensures both safety and serviceability during its lifetime.

关键词： arch dam     shape optimization     robust optimization     load uncertainty     approximation model    

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Prediction of bed load sediments using different artificial neural network models

Reza ASHEGHI, Seyed Abbas HOSSEINI

《结构与土木工程前沿（英文）》 2020年 第14卷 第2期   页码 374-386 doi: 10.1007/s11709-019-0600-0

摘要： Modeling and prediction of bed loads is an important but difficult issue in river engineering. The introduced empirical equations due to restricted applicability even in similar conditions provide different accuracies with each other and measured data. In this paper, three different artificial neural networks (ANNs) including multilayer percepterons, radial based function (RBF), and generalized feed forward neural network using five dominant parameters of bed load transport formulas for the Main Fork Red River in Idaho-USA were developed. The optimum models were found through 102 data sets of flow discharge, flow velocity, water surface slopes, flow depth, and mean grain size. The deficiency of empirical equations for this river by conducted comparison between measured and predicted values was approved where the ANN models presented more consistence and closer estimation to observed data. The coefficient of determination between measured and predicted values for empirical equations varied from 0.10 to 0.21 against the 0.93 to 0.98 in ANN models. The accuracy performance of all models was evaluated and interpreted using different statistical error criteria, analytical graphs and confusion matrixes. Although the ANN models predicted compatible outputs but the RBF with 79% correct classification rate corresponding to 0.191 network error was outperform than others.

关键词： bed load prediction     artificial neural network     modeling     empirical equations    

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标题 作者 时间 类型 操作

Centrifuge experiment and numerical analysis of an air-backed plate subjected to underwater shock loading

Zhijie HUANG, Xiaodan REN, Zuyu CHEN, Daosheng LING

期刊论文

Beneficial effect of arginine vasopressin on hemorrhagic shock through improving the vascular reactivity

LI Tao, YANG Guangming, XU Jing, LIU Jiancang, LIU Liangming

期刊论文

Expression of heat shock protein gp96 in osteosarcoma and its clinical significance

GUO Weichun, CHEN Anmin

期刊论文

Influence evaluation of loading conditions during pressurized thermal shock transients based on thermal-hydraulics

Jinya KATSUYAMA, Shumpei UNO, Tadashi WATANABE, Yinsheng LI

期刊论文

Alteration of heat shock protein 20 expression in preeclamptic patients and its effect in vascular and

Fanfan Li, Mengzhou He, Meitao Yang, Yao Fan, Yun Chen, Xi Xia, Yin Xie, Dongrui Deng

期刊论文

Estimation of composite load model with aggregate induction motor dynamic load for an isolated hybrid

Nitin Kumar SAXENA,Ashwani Kumar SHARMA

期刊论文

岩石冲击损伤演化规律数值流形方法模拟

刘红岩,吕淑然,秦四清

期刊论文

Effects on mechanical properties in electron beam welding of TC4 alloy by laser shock processing

LU Jinzhong, ZHANG Yongkang, KONG Dejun, REN Xudong, GE Tao, ZOU Shikun

期刊论文

Calculation method of load distribution on pipe threaded connections under tension load

Shoujun CHEN, Lianxin GAO, Qi AN

期刊论文

水下钻孔爆破的爆炸冲击波测试与分析

柯松林,李琳娜,司剑峰,钟冬望

期刊论文

Comparison of optimal capacitor placement methods in radial distribution system with load growth andZIP load model

Veera Venkata Satya Naryana MURTY, Ashwani KUMAR

期刊论文

化爆冲击波在90°拐角通道内的到时规律

沈俊,李永池,庞伟宾,

期刊论文

A practical multi-lane factor model of bridges based on multi-truck presence considering lane load disparities

期刊论文

Shape design of arch dams under load uncertainties with robust optimization

Fengjie TAN, Tom LAHMER

期刊论文

Prediction of bed load sediments using different artificial neural network models

Reza ASHEGHI, Seyed Abbas HOSSEINI

期刊论文